Search for the Heliospheric Termination Shock (TS) and Heliosheath (HS)

Voyager 1 continues to measure the very distant Heliospheric Magnetic Field (HMF) beyond 95 AU at ~35 North latitude. The MAG instrument data covers more than a full 22 years solar magnetic cycle. The magnitude of the observed HMF is well described, on average, by Parker's Archimedean spiral structure if due account is made for time variations of the source field strength and solar wind velocity. The V1 magnetic field observations do not provide any evidence for a field increase associated with entry into a subsonic solar wind region, such as the heliosheath is expected to be, nor an exit from this regime. We see no evidence for crossing of the Termination Shock (TS) as has been reported at ~85 AU by the LECP instrument. Merged Interaction Regions are identified by an increased HMF and associated decreases in the flux of >70 MeV/nuc cosmic rays which are then followed by a flux recovery. This CR-B relationship has been identified in V1 data and studied since 1982 when V1 was at 11 AU. The variance of HMF, a direct measure of the energy**1/2 in the HMF fluctuations, shows no significant changes associated with the alleged TS crossings in 2002–2003. Thus, the absence of any HMF increase at the entry into the heliosheath appears not to be due to the onset of mesoscale turbulence as proposed by Fisk. The TS has yet to be directly observed in-situ by the V1 MAG experiment in data through 2003

Gamma ray angular correlations following inelastic scattering of 42-MeV alpha particles from magnesium 24

Angular correlation between inelastically scattered alpha particles and gamma rays emitted in subsequent nuclear decay of magnesium 2

Perfection of materials technology for producing improved Gunn-effect devices Interim scientific report

Chemical vapor deposition of epitaxial gallium arsenid

Identification of a functional genetic variant driving racially dimorphic platelet gene expression of the thrombin receptor regulator, PCTP.

Platelet activation in response to stimulation of the Protease Activated Receptor 4 (PAR4) receptor differs by race. One factor that contributes to this difference is the expression level of Phosphatidylcholine Transfer Protein (PCTP), a regulator of platelet PAR4 function. We have conducted an expression Quantitative Trait Locus (eQTL) analysis that identifies single nucleotide polymorphisms (SNPs) linked to the expression level of platelet genes. This analysis revealed 26 SNPs associated with the expression level of PCTP at genome-wide significance (p \u3c 5×10(-8)). Using annotation from ENCODE and other public data we prioritised one of these SNPs, rs2912553, for functional testing. The allelic frequency of rs2912553 is racially-dimorphic, in concordance with the racially differential expression of PCTP. Reporter gene assays confirmed that the single nucleotide change caused by rs2912553 altered the transcriptional potency of the surrounding genomic locus. Electromobility shift assays, luciferase assays, and overexpression studies indicated a role for the megakaryocytic transcription factor GATA1. In summary, we have integrated multi-omic data to identify and functionalise an eQTL. This, along with the previously described relationship between PCTP and PAR4 function, allows us to characterise a genotype-phenotype relationship through the mechanism of gene expression

Penning collisions of laser-cooled metastable helium atoms

We present experimental results on the two-body loss rates in a magneto-optical trap of metastable helium atoms. Absolute rates are measured in a systematic way for several laser detunings ranging from -5 to -30 MHz and at different intensities, by monitoring the decay of the trap fluorescence. The dependence of the two-body loss rate coefficient $\beta$ on the excited state ($2^3P_2$) and metastable state ($2^3S_1$) populations is also investigated. From these results we infer a rather uniform rate constant $K_{sp}=(1{\pm}0.4)\times10^{-7}$ cm$^3$/s.Comment: 8 pages, 9 figures, Revte